Pregnanes
C21 steroid compounds with a 2-carbon side chain extending from the D ring. This family includes pregnenolone, progesterone derivatives, and related neurosteroids with powerful mood and social effects.
Molecules in this Family
Allopregnanolone
Allo, ALLO
The most potent endogenous GABAA modulator. FDA-approved for postpartum depression (as Brexanolone/Zulresso, 2019). Prof...
Epiallopregnanolone
Isopregnanolone, Isoallopregnanolone
The Survival Pheromone. Dramatic sensory enhancement — hyper-awareness of sights/sounds, auditory sharpening, visual enh...
Pregnenolone Sulfate
Preg-S, PS
Water-soluble pregnenolone derivative and potent NMDA enhancer / GABAA antagonist -- opposite effects to most neurostero...
THDOC
Tetrahydrodeoxycorticosterone, A-THDOC
Two forms with distinct effects. Alpha THDOC ('The Reset Pheromone'): hypnotic spotlight effect, stress elimination, mot...
Pregnenolone
Neno, Nenolone
The Charmer/Hilarity Pheromone. Creates intense magnetism, VERY strong mood elevation, giddiness, and playful/silly beha...